Anti-human CD25 IL2RA Monoclonal Antibody Biotin Conjugated, Flow Validated

Boster Bio Anti-human CD25 IL2RA Monoclonal Antibody Biotin Conjugated, Flow Validated (Catalog# FC00214-Biotin) . Tested in Flow Cytometry application (s) . This antibody reacts with Human.

Product Specifications

Background

CD25 is the alpha chain of the IL-2 receptor. It is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes that associates with CD122 to form a heterodimer that can act as a high-affinity receptor for IL-2. The IL2R gene was mapped to 10p15-p14. CD25 is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, and tumor infiltrating lymphocytes. Its soluble form, called sIL-2R may be elevated in these diseases and is occasionally used to track disease progression.

Synonyms

Interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; TAC antigen; p55; CD25; IL2RA

Gene Name

IL2RA

UniProt

P01589

Host

Mouse

Reactivity

Human

Immunogen

Influenza virus stimulated human peripheral blood mononuclear cells

Clonality

Monoclonal

Clone

Clone: Clone: 7G7B6

Conjugation

Biotin

Applications

Flow Cytometry

Field of Research

Adaptive Immunity, Cytokines, Immunology, Innate Immunity, Interleukins, T Cells

Purification

Protein A purified

Sensitivity

5ul per sample

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Dilution

User needs to optimize the dilution ratio for this antibody.

Form

Liquid

Function

Receptor for interleukin-2.

Molecular Weight

30819 MW

Shipping Conditions

Available

Storage Conditions

Store at 2-8°C. Avoid repeated freeze-thaw cycles.

Fragment

IgG2a, k

Other Gene Names

Interleukin-2 receptor subunit alpha

Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Name

Interleukin-2 receptor subunit alpha

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