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Anti-GPRC5B Antibody

Boster Bio Anti-GPRC5B Antibody (Catalog# A30826) . Tested in WB, IF, ICC, ELISA applications. This antibody reacts with Human, Rat, Mouse.

Product Specifications

Synonyms

GPRC5B; RAIG2; G-protein coupled receptor family C group 5 member B; A-69G12.1; Retinoic acid-induced gene 2 protein; RAIG-2

Gene Name

GPRC5B

UniProt

Q9NZH0

Host

Rabbit

Reactivity

Human, Rat, Mouse

Immunogen

A peptide derived from human GPRC5B. Immunogen sequence location: 61 - 110

Clonality

Polyclonal

Tissue Specificity

Expression is high in kidney, pancreas, and testis, medium in brain, heart, prostate, small intestine, and spleen, low in liver, placenta, skeletal muscle, colon, ovary, and thymus, and not detectable in lung and peripheral leukocyte. According to PubMed:10945465, highly expressed in most brain areas examined, with the highest levels observed in corpus callosum, caudate nucleus, putamen, substantia nigra, thalamus, hippocampus, and spinal chord as well as in dorsal root ganglia (DRG) . In the periphery, expression levels are relatively low, compared to the CNS, with the strongest expression detected in pancreas, testis, uterus, and stomach.

Applications

WB, IF, ICC, ELISA

Field of Research

G Protein Signaling, More Gpcr, Neuroscience, Neurotransmission, Receptors / Channels, Sensory System, Signal Transduction, Signaling Pathway, Visual System

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.

Molecular Weight

44795 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

G-protein coupled receptor family C group 5 member B

Subcellular Location

Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi- pass membrane protein. Localized in the plasma membrane and perinuclear vesicles.

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