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Anti-GPBAR Antibody

Boster Bio Anti-GPBAR Antibody (Catalog# A30825) . Tested in IF, ICC, ELISA applications. This antibody reacts with Human, Rat, Mouse.

Product Specifications

Synonyms

GPBAR1; TGR5; G-protein coupled bile acid receptor 1; G-protein coupled receptor GPCR19; hGPCR19; Membrane-type receptor for bile acids; M-BAR; hBG37; BG37

Gene Name

GPBAR1

UniProt

Q8TDU6

Host

Rabbit

Reactivity

Human, Rat, Mouse

Immunogen

A peptide derived from human GPBAR. Immunogen sequence location: 22221

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed. Expressed at higher level in spleen and placenta. Expressed at lower level in other tissues. In digestive tissues, it is expressed in stomach, duodenum, ileocecum, ileum, jejunum, ascending colon, transverse colon, descending colon, cecum and liver, but not in esophagus and rectum.

Applications

IF, ICC, ELISA

Field of Research

G Protein Signaling, Signal Transduction, Signaling Pathway

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids.

Molecular Weight

35248 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A30825

Product MSDS

https://www.bosterbio.com/msds?sku=A30825

Fragment

Rabbit IgG

Other Gene Names

G-protein coupled bile acid receptor 1

Subcellular Location

Cell membrane; Multi-pass membrane protein.

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