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Anti-GPR132/G2A Antibody

Boster Bio Anti-GPR132/G2A Antibody (Catalog# A30804) . Tested in WB, IHC-P, IF, ICC, ELISA applications. This antibody reacts with Human, Rat, Mouse.

Product Specifications

Synonyms

GPR132; G2A; Probable G-protein coupled receptor 132; G2 accumulation protein

Gene Name

GPR132

UniProt

Q9UNW8

Host

Rabbit

Reactivity

Human, Rat, Mouse

Immunogen

A peptide derived from human GPR132. Immunogen sequence location: 311 - 360

Clonality

Polyclonal

Tissue Specificity

Highly expressed in macrophages and hematopoietic tissues rich in lymphocytes, like spleen and thymus. Weakly expressed in heart and lung. In atherosclerotic plaques, expression is observed around the lipid core and at the shoulder region.

Applications

WB, IHC-P, IF, ICC, ELISA

Field of Research

G Protein Signaling, Signal Transduction, Signaling Pathway

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Sensitivity

<15pg/ml

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

May be a receptor for oxidized free fatty acids derived from linoleic and arachidonic acids such as 9- hydroxyoctadecadienoic acid (9-HODE) . Activates a G alpha protein, most likely G alpha (q) . May be involved in apoptosis. Functions at the G2/M checkpoint to delay mitosis. May function as a sensor that monitors the oxidative states and mediates appropriate cellular responses such as secretion of paracrine signals and attenuation of proliferation. May mediate ths accumulation of intracellular inositol phosphates at acidic pH through proton- sensing activity.

Molecular Weight

42499 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Probable G-protein coupled receptor 132

Subcellular Location

Cell membrane; Multi-pass membrane protein. Internalized and accumulated in endosomal compartments. LPC triggers the relocalization from the endosomal compartment to the cell surface (By similarity) .

Frequently Asked Questions

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