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Anti-GPR109 HCAR3 Antibody

Boster Bio Anti-GPR109 HCAR3 Antibody (Catalog# A30790) . Tested in WB, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

HCAR3; GPR109B; HCA3; HM74B; NIACR2; Hydroxycarboxylic acid receptor 3; G-protein coupled receptor 109B; G-protein coupled receptor HM74; G-protein coupled receptor HM74B; Niacin receptor 2; Nicotinic acid receptor 2; HCAR2; GPR109A; HCA2

Gene Name

HCAR3

UniProt

P49019

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from human GPR109. Immunogen sequence location: 285 - 334

Clonality

Polyclonal

Tissue Specificity

Expression largely restricted to adipose tissue and spleen.

Applications

WB, IF, ICC, ELISA

Field of Research

G Protein Signaling, Signal Transduction, Signaling Pathway

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet.

Molecular Weight

44478 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Hydroxycarboxylic acid receptor 3

Subcellular Location

Cell membrane; Multi-pass membrane protein.

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