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Anti-IL29 Antibody

Boster Bio Anti-IL29 Antibody (Catalog# A30780) . Tested in WB, ELISA applications. This antibody reacts with Human, Rat, Mouse.

Product Specifications

Synonyms

IL29; IFNL1; ZCYTO21; Interleukin-29; IL-29; Cytokine Zcyto21; Interferon lambda-1; IFN-lambda-1

Gene Name

IFNL1

UniProt

Q8IU54

Host

Rabbit

Reactivity

Human, Rat, Mouse

Immunogen

A peptide derived from the Internal region of human IL29. Immunogen sequence location: 121 - 170

Clonality

Polyclonal

Applications

WB, ELISA

Field of Research

Cytokines, Immunology, Innate Immunity, Interleukins

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using peptide.

Sensitivity

<10pg/ml

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN- stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type- selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.

Molecular Weight

21898 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Interferon lambda-1

Subcellular Location

Secreted.

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