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Anti-RAB7L1 RAB29 Antibody

Boster Bio Anti-RAB7L1 RAB29 Antibody (Catalog# A30753) . Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

RAB7L1; Ras-related protein Rab-7L1; Rab-7-like protein 1

Gene Name

RAB29

UniProt

O14966

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from human RAB7L1. Immunogen sequence location: 115 - 164

Clonality

Polyclonal

Tissue Specificity

Ubiquitous.

Applications

WB, ELISA

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Rab GTPase key regulator in vesicle trafficking. Essential for maintaining the integrity of the endosome-trans- Golgi network structure. Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS) . May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection.

Molecular Weight

23155 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Ras-related protein Rab-7L1

Subcellular Location

Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus. Golgi apparatus, trans-Golgi network. Vacuole. Cytoplasm, cytoskeleton. Colocalizes with LRRK2 along tubular structures emerging from Golgi apparatus (By similarity) . Colocalizes with GM130 at the Golgi apparatus (PubMed:22042847) . Colocalizes with dynamic tubules emerging from and retracting to the Golgi apparatus (PubMed:22042847) . Colocalizes with TGN46 at the trans-Golgi network (TGN) (PubMed:24788816) . In Salmonella enterica serovar Typhi (S.Typhi) infected epithelial cells, is recruited and colocalized with both S.Typhi-containing vacuoles and dynamic tubules as well as those emerging from the vacuole toward the cell periphery (PubMed:22042847) .

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