What is the catalog number for Anti-PVRL3 NECTIN3 Antibody?

The catalog number for Anti-PVRL3 NECTIN3 Antibody is A30746.

What sizes are available for Anti-PVRL3 NECTIN3 Antibody?

Anti-PVRL3 NECTIN3 Antibody is available in the following size(s): 100 µL.

Is Anti-PVRL3 NECTIN3 Antibody in stock?

Anti-PVRL3 NECTIN3 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-PVRL3 NECTIN3 Antibody?

The safety data sheet for Anti-PVRL3 NECTIN3 Antibody is available here: https://www.bosterbio.com/msds?sku=A30746.

Anti-PVRL3 NECTIN3 Antibody

Boster Bio Anti-PVRL3 NECTIN3 Antibody (Catalog# A30746) . Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

PVRL3; PRR3; Poliovirus receptor-related protein 3; CDw113; Nectin-3; CD113

Gene Name

NECTIN3

UniProt

Q9NQS3

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from the Internal region of human PVRL3. Immunogen sequence location: 311 - 360

Clonality

Polyclonal

Tissue Specificity

Predominantly expressed in testis and placenta as well as in many cell lines, including epithelial cell lines.

Applications

WB, ELISA

Field of Research

Host-Virus Interaction, Immunoglobulins, Immunology, Interspecies Interaction, Microbiology, Receptors

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using peptide.

Sensitivity

>5000 cells

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis- mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.