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Anti-KCNJ2/Kir2.1 Antibody

Boster Bio Anti-KCNJ2/Kir2.1 Antibody (Catalog# A30730) . Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Rat.

Product Specifications

Synonyms

KCNJ2; IRK1; Inward rectifier potassium channel 2; Cardiac inward rectifier potassium channel; Inward rectifier K (+) channel Kir2.1; IRK-1; hIRK1; Potassium channel; inwardly rectifying subfamily J member 2

Gene Name

KCNJ2

UniProt

P63252

Host

Rabbit

Reactivity

Human, Rat

Immunogen

A peptide derived from human KCNJ2. Immunogen sequence location: 81-130

Clonality

Polyclonal

Tissue Specificity

Heart, brain, placenta, lung, skeletal muscle, and kidney. Diffusely distributed throughout the brain.

Applications

WB, IHC-P, IF (paraffin), ELISA

Field of Research

Neuroscience, Neurotransmission, Potassium Channels, Receptors / Channels

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium or cesium.

Molecular Weight

48288 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A30730

Product MSDS

https://www.bosterbio.com/msds?sku=A30730

Fragment

Rabbit IgG

Other Gene Names

Inward rectifier potassium channel 2

Subcellular Location

Membrane; Multi-pass membrane protein. Membrane; Lipid-anchor.

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