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Anti-TTF-1 NKX2-1 Antibody

Boster Bio Anti-TTF-1 NKX2-1 Antibody (Catalog# A30726) . Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

NKX2-1; NKX2A; TITF1; TTF1; Homeobox protein Nkx-2.1; Homeobox protein NK-2 homolog A; Thyroid nuclear factor 1; Thyroid transcription factor 1; TTF-1

Gene Name

NKX2-1

UniProt

P43699

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from human TTF-1. Immunogen sequence location: 27 - 76

Clonality

Polyclonal

Tissue Specificity

Thyroid and lung.

Applications

WB, ELISA

Field of Research

Epigenetics and Nuclear Signaling, Transcription

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Sensitivity

>5000 cells

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1 (By similarity) .

Molecular Weight

38596 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Homeobox protein Nkx-2.1

Subcellular Location

Nucleus.

Frequently Asked Questions

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