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Anti-HLA-DOA/Hla Doa Antibody

Boster Bio Anti-HLA-DOA/Hla Doa Antibody (Catalog# A30721) . Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human.

Product Specifications

Synonyms

HLA-DOA; HLA-DNA; HLA-DZA; HLA class II histocompatibility antigen; DO alpha chain; MHC DN-alpha; MHC DZ alpha; MHC class II antigen DOA

Gene Name

HLA-DOA

UniProt

P06340

Host

Rabbit

Reactivity

Human

Immunogen

A peptide derived from human HLA-DOA. Immunogen sequence location: 71-120

Clonality

Polyclonal

Applications

WB, IHC-P, IF (paraffin), ELISA

Field of Research

Adaptive Immunity, Immunology

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Sensitivity

<12pg/ml

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. Modifies peptide exchange activity of HLA-DM.

Molecular Weight

27599 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

HLA class II histocompatibility antigen, DO alpha chain

Subcellular Location

Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Complexes with HLA-DM molecule during intracellular transport and in endosomal/lysosomal compartments. Heterotetramerization is necessary to exit the ER.

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