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Anti-RAD RRAD Antibody

Boster Bio Anti-RAD RRAD Antibody (Catalog# A30715) . Tested in WB, IHC-P, IF, ICC, ELISA applications. This antibody reacts with Human, Rat, Mouse.

Product Specifications

Synonyms

RRAD; RAD; GTP-binding protein RAD; RAD1; Ras associated with diabetes

Gene Name

RRAD

UniProt

P55042

Host

Rabbit

Reactivity

Human, Rat, Mouse

Immunogen

A peptide derived from human RAD. Immunogen sequence location: 41-90

Clonality

Polyclonal

Tissue Specificity

Most abundantly expressed in the heart. Also found in the skeletal muscle and lung. Lesser amounts in placenta and kidney. Also detected in adipose tissue. Overexpressed in muscle of type II diabetic humans.

Applications

WB, IHC-P, IF, ICC, ELISA

Field of Research

Cardiovascular, G Protein Signaling, Hypertrophy, Signal Transduction, Signaling Pathway, Small G Proteins

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca (2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha- 1C trafficking to the cell membrane (By similarity) . Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D.

Molecular Weight

33245 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

GTP-binding protein RAD

Subcellular Location

Cell membrane.

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