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Anti-POFUT2 Antibody

Boster Bio Anti-POFUT2 Antibody (Catalog# A30701) . Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

POFUT2; C21orf80; FUT13; KIAA0958; GDP-fucose protein O-fucosyltransferase 2; Peptide-O-fucosyltransferase 2; O-FucT-2

Gene Name

POFUT2

UniProt

Q9Y2G5

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A peptide derived from human POFUT2. Immunogen sequence location: 361-410

Clonality

Polyclonal

Tissue Specificity

Isoform A is expressed in fetal liver and peripheral blood lymphocytes.Isoform B is expressed in spleen, lung, testis, bone marrow, thymus, pancreas, prostate, fetal brain, fetal liver and fetal kidney.Isoform C is expressed in brain, heart, spleen, liver, lung, stomach, testis, placenta, skin, thymus, pancreas, mammary gland, prostate, fetal brain, fetal liver and fetal heart.

Applications

IHC-P, IF (paraffin), ELISA

Field of Research

Energy Metabolism, Energy Transfer Pathways, Metabolic Signaling Pathways, Metabolism, Organelles, Pathways and Processes, Signal Transduction, Subcellular Markers, Tags & Cell Markers

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X (2,3) -S/T-C2-X (2) -G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of several protein families including the ADAMTS family, the thrombosporin (TSP) and spondin families. The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition (EMT), maintaining the correct patterning of mesoderm and localization of the definite endoderm (By similarity) . Required for the proper secretion of ADAMTS family members such as ADAMSL1 and ADAMST13.

Molecular Weight

49976 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

GDP-fucose protein O-fucosyltransferase 2

Subcellular Location

Endoplasmic reticulum. Golgi apparatus. Mainly located in the endoplasmic reticulum.

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