Anti-EIF3K Antibody

Boster Bio Anti-EIF3K Antibody (Catalog# A30681) . Tested in WB, ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

EIF3K; EIF3S12; ARG134; HSPC029; MSTP001; PTD001; Eukaryotic translation initiation factor 3 subunit K; eIF3k; Eukaryotic translation initiation factor 3 subunit 12; Muscle-specific gene M9 protein; PLAC-24; eIF-3 p25; eIF-3 p28

Gene Name

EIF3K

UniProt

Q9UBQ5

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A peptide derived from human EIF3K. Immunogen sequence location: 61-110

Clonality

Polyclonal

Tissue Specificity

Ubiquitous, with the highest levels of expression in brain, testis and kidney.

Applications

WB, ELISA

Field of Research

DNA/RNA, Epigenetics and Nuclear Signaling, Neuroscience, Neurotransmission, Receptors / Channels, Translation

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC) . The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.