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Anti-ELOVL5 Antibody

Boster Bio Anti-ELOVL5 Antibody (Catalog# A30674) . Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Rat, Mouse.

Product Specifications

Synonyms

ELOVL5; ELOVL2; Elongation of very long chain fatty acids protein 5;3-keto acyl-CoA synthase ELOVL5; ELOVL fatty acid elongase 5; ELOVL FA elongase 5; Fatty acid elongase 1; hELO1

Gene Name

ELOVL5

UniProt

Q9NYP7

Host

Rabbit

Reactivity

Human, Rat, Mouse

Immunogen

A peptide derived from human ELOVL5. Immunogen sequence location: 250-299

Clonality

Polyclonal

Tissue Specificity

Ubiquitous. Highly expressed in the adrenal gland and testis. Weakly expressed in prostate, lung and brain. Expressed in the cerebellum.

Applications

WB, IHC-P, IF (paraffin), ELISA

Field of Research

Cardiovascular, Fatty Acid Oxidation, Fatty Acids, Lipid Metabolism, Lipids/Lipoproteins, Metabolism, Pathways and Processes, Redox Metabolism, Signal Transduction

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3 (n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.

Molecular Weight

35293 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Elongation of very long chain fatty acids protein 5

Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell projection, dendrite. In Purkinje cells, the protein localizes to the soma and proximal portion of the dendritic tree.

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