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Anti-MARCH4 MARCH4; Antibody

Boster Bio Anti-MARCH4 MARCH4; Antibody (Catalog# A30662) . Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

MARCH4; KIAA1399; RNF174; E3 ubiquitin-protein ligase MARCH4; Membrane-associated RING finger protein 4; Membrane-associated RING-CH protein IV; MARCH-IV; RING finger protein 174

Gene Name

MARCH4

UniProt

Q9P2E8

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A peptide derived from human MARCH4. Immunogen sequence location: 301-350

Clonality

Polyclonal

Tissue Specificity

Expressed in brain and placenta.

Applications

IHC-P, IF (paraffin), ELISA

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Molecular Weight

45528 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

E3 ubiquitin-protein ligase MARCH4

Subcellular Location

Golgi apparatus membrane; Multi-pass membrane protein.

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