Anti-MARCH2 MARCH2; Antibody
Boster Bio Anti-MARCH2 MARCH2; Antibody (Catalog# A30660) . Tested in IHC-P, IF, ICC, ELISA applications. This antibody reacts with Human, Rat, Mouse.
Product Specifications
Synonyms
MARCH2; RNF172; HSPC240; E3 ubiquitin-protein ligase MARCH2; Membrane-associated RING finger protein 2; Membrane-associated RING-CH protein II; MARCH-II; RING finger protein 172
Gene Name
MARCH2
UniProt
Q9P0N8
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
A peptide derived from human MARCH2. Immunogen sequence location: 191-240
Clonality
Polyclonal
Tissue Specificity
Broadly expressed.
Applications
IHC-P, IF, ICC, ELISA
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Form
Liquid
Function
E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May be involved in endosomal trafficking through interaction with STX6.
Molecular Weight
26995 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
Rabbit IgG
Other Gene Names
E3 ubiquitin-protein ligase MARCH2
Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein.
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