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Anti-Condensin complex subunit 2 NCAPH Antibody

Boster Bio Anti-Condensin complex subunit 2 NCAPH Antibody (Catalog# A30627) . Tested in WB, ELISA applications. This antibody reacts with Human, Rat, Mouse.

Product Specifications

Synonyms

NCAPH; BRRN; BRRN1; CAPH; KIAA0074; Condensin complex subunit 2; Barren homolog protein 1; Chromosome-associated protein H; hCAP-H; Non-SMC condensin I complex subunit H; XCAP-H homolog

Gene Name

NCAPH

UniProt

Q15003

Host

Rabbit

Reactivity

Human, Rat, Mouse

Immunogen

A peptide derived from human NCAPH. Immunogen sequence location: 441-490

Clonality

Polyclonal

Tissue Specificity

Widely expressed at low level. Expressed in proliferating cells.

Applications

WB, ELISA

Field of Research

Cell Biology, Cell Cycle, Cell Division, Chromosome Structure, Epigenetics and Nuclear Signaling

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

Molecular Weight

82563 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A30627

Product MSDS

https://www.bosterbio.com/msds?sku=A30627

Fragment

Rabbit IgG

Other Gene Names

Condensin complex subunit 2

Subcellular Location

Nucleus. Cytoplasm. Chromosome. In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.
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