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Anti-CTDSP1 Antibody

Boster Bio Anti-CTDSP1 Antibody (Catalog# A30598) . Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

CTDSP1; NIF3; NLIIF; SCP1; Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1; Nuclear LIM interactor-interacting factor 3; NLI-IF; NLI-interacting factor 3; Small C-terminal domain phosphatase 1; SCP1; Small CTD ph

Gene Name

CTDSP1

UniProt

Q9GZU7

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from human CTDSP1. Immunogen sequence location: 1-50

Clonality

Polyclonal

Tissue Specificity

Expression is restricted to non-neuronal tissues. Highest expression in skeletal muscle, spleen, lung and placenta.

Applications

WB, IHC-P, IF (paraffin), ELISA

Field of Research

Epigenetics and Nuclear Signaling, Nuclear Signaling, Nuclear Signaling Pathways, Pol II Transcription, Polymerase Associated Factors, Signal Transduction, Signaling Pathway, Transcription

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.

Molecular Weight

29203 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

Subcellular Location

Nucleus. Colocalizes with RNA polymerase II.

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