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Anti-CHST10/Hnk 1St Antibody

Boster Bio Anti-CHST10/Hnk 1St Antibody (Catalog# A30586) . Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

CHST10; Carbohydrate sulfotransferase 10; HNK-1 sulfotransferase; HNK-1ST; HNK1ST; HuHNK-1ST

Gene Name

CHST10

UniProt

O43529

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from human CHST10. Immunogen sequence location: 191-240

Clonality

Polyclonal

Tissue Specificity

In fetal tissues, it is predominantly expressed in brain, and weakly expressed in lung, kidney and liver. In adult, it is highly expressed in brain, testis, ovary, expressed at intermediate level in heart, pancreas, skeletal muscle, spleen and thymus, and weakly expressed in other tissues. In brain, it is expressed at higher level in the frontal lobe.

Applications

WB, IHC-P, IF (paraffin), ELISA

Field of Research

Cancer, Energy Metabolism, Energy Transfer Pathways, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Sensitivity

<10pg/ml

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Catalyzes the transfer of sulfate to position 3 of terminal glucuronic acid of both protein- and lipid-linked oligosaccharides. Participates in biosynthesis of HNK-1 carbohydrate structure, a sulfated glucuronyl-lactosaminyl residue carried by many neural recognition molecules, which is involved in cell interactions during ontogenetic development and in synaptic plasticity in the adult. May be indirectly involved in synapse plasticity of the hippocampus, via its role in HNK-1 biosynthesis.

Molecular Weight

42207 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Carbohydrate sulfotransferase 10

Subcellular Location

Golgi apparatus membrane; Single-pass type II membrane protein.

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