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Anti-DUS2/Dus2LL Antibody

Boster Bio Anti-DUS2/Dus2LL Antibody (Catalog# A30563) . Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

DUS2L; DUS2; tRNA-dihydrouridine (20) synthase [NAD (P) +]-like; Up-regulated in lung cancer protein 8; URLC8; tRNA-dihydrouridine synthase 2-like; hDUS2

Gene Name

DUS2

UniProt

Q9NX74

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A peptide derived from human DUS2L. Immunogen sequence location: 421-470

Clonality

Polyclonal

Tissue Specificity

Weak expression in heart, placenta and skeletal muscle. Up-regulated in most lung cancer cells (at protein level) .

Applications

WB, IHC-P, IF (paraffin), ELISA

Field of Research

DNA/RNA, Epigenetics and Nuclear Signaling, RNA Processing, Translation

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR.

Molecular Weight

55050 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

TRNA-dihydrouridine (20) synthase [NAD (P) +]-like

Subcellular Location

Cytoplasm. Endoplasmic reticulum. Mainly at the endoplasmic reticulum.

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