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Anti-RHG07 DLC1 Antibody

Boster Bio Anti-RHG07 DLC1 Antibody (Catalog# A30552) . Tested in IHC-P, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

DLC1; ARHGAP7; KIAA1723; STARD12; Rho GTPase-activating protein 7; Deleted in liver cancer 1 protein; DLC-1; HP protein; Rho-type GTPase-activating protein 7; START domain-containing protein 12; StARD12; StAR-related lipid transfer protein

Gene Name

DLC1

UniProt

Q96QB1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from human RHG07. Immunogen sequence location: 61-110

Clonality

Polyclonal

Tissue Specificity

Highest level of expression in the spleen, with rather lower levels in prostate, testis, ovary, small intestine and colon, but none in the thymus.

Applications

IHC-P, IF, ICC, ELISA

Field of Research

Cancer, Cancer Susceptibility, Cell Type Markers, Epigenetics and Nuclear Signaling, G Protein Signaling, Oncoproteins/Suppressors, Ras Family, Signal Transduction, Signaling Pathway, Small G Proteins, Tags & Cell Markers, Transcription, Tumor Associated, Tumor Suppressors

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.

Molecular Weight

170591 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Rho GTPase-activating protein 7

Subcellular Location

Cytoplasm. Cell junction, focal adhesion. Membrane; Peripheral membrane protein. Colocalizes with EF1A1 at actin-rich regions in the cell periphery.

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