Anti-MEKKK 1 Antibody

Boster Bio Anti-MEKKK 1 Antibody (Catalog# A30542) . Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

MAP4K1; HPK1; Mitogen-activated protein kinase kinase kinase kinase 1; Hematopoietic progenitor kinase; MAPK/ERK kinase kinase kinase 1; MEK kinase kinase 1; MEKKK 1

Gene Name

MAP4K1

UniProt

Q92918

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A peptide derived from human MEKKK 1. Immunogen sequence location: 371-420

Clonality

Polyclonal

Tissue Specificity

Expressed primarily in hematopoietic organs, including bone marrow, spleen and thymus. Also expressed at very low levels in lung, kidney, mammary glands and small intestine.

Applications

WB, IHC-P, IF (paraffin), ELISA

Field of Research

G Protein Signaling, MAPK Pathway, Protein Phosphorylation, Regulators, Ser/Thr Kinases, Signal Transduction, Signaling Pathway, Small G Proteins

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Sensitivity

<10pg/ml

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Serine/threonine-protein kinase, which may play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in hematopoietic lineage decisions and growth regulation. Able to autophosphorylate.