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Anti-ACTR-1C Antibody

Boster Bio Anti-ACTR-1C Antibody (Catalog# A30526) . Tested in IHC-P, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

ACVR1C; ALK7; Activin receptor type-1C; Activin receptor type IC; ACTR-IC; Activin receptor-like kinase 7; ALK-7

Gene Name

ACVR1C

UniProt

Q8NER5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from human ACTR-1C. Immunogen sequence location: 201-250

Clonality

Polyclonal

Tissue Specificity

Present in pancreas, heart, colon, small intestine, ovary and the hippocampus, medulla oblongata and putamen of the brain. Isoform 1, isoform 2, isoform 3 and isoform 4 are all expressed in the placenta throughout pregnancy.

Applications

IHC-P, IF, ICC, ELISA

Field of Research

Cancer, Epigenetics and Nuclear Signaling, Growth Factors, Nuclear Signaling, Nuclear Signaling Pathways, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction, Signaling Pathway

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Sensitivity

<50pg/ml

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.

Molecular Weight

54871 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Activin receptor type-1C

Subcellular Location

Membrane; Single-pass type I membrane protein.

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