What is the catalog number for Anti-MOL1A MOB1B Antibody?

The catalog number for Anti-MOL1A MOB1B Antibody is A30515.

What sizes are available for Anti-MOL1A MOB1B Antibody?

Anti-MOL1A MOB1B Antibody is available in the following size(s): 100 µL.

Is Anti-MOL1A MOB1B Antibody in stock?

Anti-MOL1A MOB1B Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-MOL1A MOB1B Antibody?

The safety data sheet for Anti-MOL1A MOB1B Antibody is available here: https://www.bosterbio.com/msds?sku=A30515.

Anti-MOL1A MOB1B Antibody

Boster Bio Anti-MOL1A MOB1B Antibody (Catalog# A30515) . Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Monkey.

Product Specifications

Synonyms

MOB1B; MOB4A; MOBKL1A; MOB kinase activator 1B; Mob1 homolog 1A; Mob1A; Mob1B; Mps one binder kinase activator-like 1A

Gene Name

MOB1B

UniProt

Q7L9L4

Host

Rabbit

Reactivity

Human, Mouse, Monkey

Immunogen

A peptide derived from human MOL1A. Immunogen sequence location: 101-150

Clonality

Polyclonal

Tissue Specificity

Adrenal gland, bone marrow, brain, lung, placenta, prostate, salivary gland, skeletal muscle, testis, thymus, thyroid gland, uterus, colon with mucosa, fetal brain and fetal liver.

Applications

WB, IHC-P, IF (paraffin), ELISA

Field of Research

Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38L.