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Anti-STEAP4/Stamp2 Antibody

Boster Bio Anti-STEAP4/Stamp2 Antibody (Catalog# A30510) . Tested in IHC-P, IF, ICC, ELISA applications. This antibody reacts with Human, Rat, Mouse.

Product Specifications

Synonyms

STEAP4; STAMP2; TNFAIP9; Metalloreductase STEAP4; Six-transmembrane epithelial antigen of prostate 4; SixTransMembrane protein of prostate 2; Tumor necrosis factor; alpha-induced protein 9

Gene Name

STEAP4

UniProt

Q687X5

Host

Rabbit

Reactivity

Human, Rat, Mouse

Immunogen

A peptide derived from human STEAP4. Immunogen sequence location: 201-250

Clonality

Polyclonal

Tissue Specificity

Ubiquitous. Highly expressed in adipose tissue. Expressed in placenta, lung, heart and prostate. Detected at lower levels in liver, skeletal muscle, pancreas, testis and small intestine. Highly expressed in joints of patients with rheumatoid arthritis and localized with CD68 cells, a marker for macrophages.

Applications

IHC-P, IF, ICC, ELISA

Field of Research

Cancer, Energy Metabolism, Energy Transfer Pathways, Metabolic Signaling Pathways, Metabolism, Obesity, Pathways and Processes, Tumor Antigens, Tumor Biomarkers, Tumor Immunology, Tumor-Associated Antigens

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Metalloreductase that has the ability to reduce both Fe (3+) to Fe (2+) and Cu (2+) to Cu (1+) . Uses NAD (+) as acceptor. Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses (By similarity) . Associated with obesity and insulin-resistance. Involved in inflammatory arthritis, through the regulation of inflammatory cytokines. Inhibits anchorage-independent cell proliferation.

Molecular Weight

51981 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Metalloreductase STEAP4

Subcellular Location

Cell membrane. Golgi apparatus membrane; Multi-pass membrane protein.

Frequently Asked Questions

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