Anti-STEA3 Antibody

Boster Bio Anti-STEA3 Antibody (Catalog# A30509) . Tested in WB, IHC-P, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

STEAP3; TSAP6; Metalloreductase STEAP3; Dudulin-2; Six-transmembrane epithelial antigen of prostate 3; Tumor suppressor-activated pathway protein 6; hTSAP6; pHyde; hpHyde

Gene Name

STEAP3

UniProt

Q658P3

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from human STEA3. Immunogen sequence location: 421-470

Clonality

Polyclonal

Tissue Specificity

Expressed in adult bone marrow, placenta, liver, skeletal muscle and pancreas. Down-regulated in hepatocellular carcinoma.

Applications

WB, IHC-P, IF, ICC, ELISA

Field of Research

Cofactors, Vitamins/Minerals, Metabolism, Pathways and Processes, Signal Transduction, Vitamins/Minerals

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe (3+) to Fe (2+) . Can also reduce of Cu (2+) to Cu (1+), suggesting that it participates in copper homeostasis. Uses NADP (+) as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.