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Anti-DYR1A DYRK1A Antibody

Boster Bio Anti-DYR1A DYRK1A Antibody (Catalog# A30487) . Tested in WB, IHC-P, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

DYRK1A; DYRK; MNB; MNBH; Dual specificity tyrosine-phosphorylation-regulated kinase 1A; Dual specificity YAK1-related kinase; HP86; Protein kinase minibrain homolog; MNBH; hMNB

Gene Name

DYRK1A

UniProt

Q13627

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from human DYR1A. Immunogen sequence location: 21-70

Clonality

Polyclonal

Tissue Specificity

Ubiquitous. Highest levels in skeletal muscle, testis, fetal lung and fetal kidney.

Applications

WB, IHC-P, IF, ICC, ELISA

Field of Research

Neurogenesis, Neurology Process, Neuroscience

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Modulates alternative splicing by phosphorylating the splice factor SRSF6 (By similarity) . Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates such as CRY2, FOXO1, SRSF6 and SIRT1. Exhibits a sugstrate preference for proline at position P+1 and arginine at position P-3.

Molecular Weight

85584 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Dual specificity tyrosine-phosphorylation-regulated kinase 1A

Subcellular Location

Nucleus speckle.

Curated Selection

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