Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-KLF Antibody

Boster Bio Anti-KLF Antibody (Catalog# A30483) . Tested in WB, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

KLF1; EKLF; Krueppel-like factor 1; Erythroid krueppel-like transcription factor; EKLF; KLF5; BTEB2; CKLF; IKLF; Krueppel-like factor 5; Basic transcription element-binding protein 2; BTE-binding protein 2; Colon krueppel-like factor; GC-bo

Gene Name

KLF1

UniProt

Q13351

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from human KLF. Immunogen sequence location: 291-340

Clonality

Polyclonal

Tissue Specificity

Expression restricted to adult bone marrow and fetal liver. Not expressed in myeloid nor lymphoid cell lines.

Applications

WB, IF, ICC, ELISA

Field of Research

2339, Domain Families, Epigenetics and Nuclear Signaling, Krueppel Like Factor, Transcription, Zinc Finger

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Sensitivity

>5000 cells

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Transcription regulator of erythrocyte development that probably serves as a general switch factor during erythropoiesis. Is a dual regulator of fetal-to-adult globin switching. Binds to the CACCC box in the beta-globin gene promoter and acts as a preferential activator of this gene. Furthermore, it binds to the BCL11A promoter and activates expression of BCL11A, which in turn represses the HBG1 and HBG2 genes. This dual activity ensures that, in most adults, fetal hemoglobin levels are low. Able to activate CD44 and AQP1 promoters. When sumoylated, acts as a transcriptional repressor by promoting interaction with CDH2/MI2beta and also represses megakaryocytic differentiation.

Molecular Weight

38221 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Krueppel-like factor 1

Subcellular Location

Nucleus. Colocalizes with SUMO1 in nuclear speckles.

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

TTC37 AAV siRNA Pooled Vector
48693161 1.0 µg

TTC37 AAV siRNA Pooled Vector

Sign In for Pricing
View Details
LY96 ELISA Kit (Human)
OKCD00545-96W 96 Well

LY96 ELISA Kit (Human)

Sign In for Pricing
View Details
SLC16A10 Antibody (C-term)
MBS9205038-01 0.08 mL

SLC16A10 Antibody (C-term)

Sign In for Pricing
View Details
SLC16A10 Antibody (C-term)
MBS9205038-02 0.4 mL

SLC16A10 Antibody (C-term)

Sign In for Pricing
View Details
SLC16A10 Antibody (C-term)
MBS9205038-03 5x 0.4 mL

SLC16A10 Antibody (C-term)

Sign In for Pricing
View Details
Human ARHGEF7 ELISA Kit
orb552231-01 48 Tests

Human ARHGEF7 ELISA Kit

Sign In for Pricing
View Details