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Anti-NKX3.1 Antibody

Boster Bio Anti-NKX3.1 Antibody (Catalog# A30460) . Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Rat, Mouse.

Product Specifications

Synonyms

NKX3-1; NKX3.1; NKX3A; Homeobox protein Nkx-3.1; Homeobox protein NK-3 homolog A

Gene Name

NKX3-1

UniProt

Q99801

Host

Rabbit

Reactivity

Human, Rat, Mouse

Immunogen

A peptide derived from human NKX3-1. Immunogen sequence location: 1-50

Clonality

Polyclonal

Tissue Specificity

Highly expressed in the prostate and, at a lower level, in the testis.

Applications

WB, IHC-P, IF (paraffin), ELISA

Field of Research

Developmental Families, Domain Families, Epigenetics and Nuclear Signaling, Transcription, Transcription Factors

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Sensitivity

>5000 cells

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.

Molecular Weight

26350 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Homeobox protein Nkx-3.1

Subcellular Location

Nucleus.

Frequently Asked Questions

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