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Anti-Vinculin VCL Antibody

Boster Bio Anti-Vinculin VCL Antibody (Catalog# A30448) . Tested in WB, IHC-P, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

VCL; Vinculin; Metavinculin

Gene Name

VCL

UniProt

P18206

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from human Vinculin. Immunogen sequence location: 786-835

Clonality

Polyclonal

Tissue Specificity

Metavinculin is muscle-specific.

Applications

WB, IHC-P, IF, ICC, ELISA

Field of Research

Actin Binding Proteins, Actin, etc., Cardiovascular, Contractility, Cytoskeleton, Cytoskeleton/ECM, Microfilaments, Signal Transduction

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Actin filament (F-actin) -binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell- surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.

Molecular Weight

123799 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A30448

Product MSDS

https://www.bosterbio.com/msds?sku=A30448

Fragment

Rabbit IgG

Other Gene Names

Vinculin

Subcellular Location

Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, focal adhesion.Cytoplasmic face of adhesion plaques. Recruitment to cell-cell junctions occurs in a myosin II- dependent manner. Interaction with CTNNB1 is necessary for its localization to the cell-cell junctions (By similarity) . Colocalizes with LIMD1 in the focal adhesions.
Curated Selection

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