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Anti-SPANX-C Antibody

Boster Bio Anti-SPANX-C Antibody (Catalog # A14601) . Tested in ELISA, WB applications. This antibody reacts with Human.

Product Specifications

Background

This antibody is suitable for Cancer, Immunology and Nuclear Signaling research. Human Sperm Proteins Associated with the Nucleus on X-chromosome (SPANX) are relatively low molecular weight cytoplasmic proteins found in testis and sperm. Their expression in other tissues indicates malignancies. Family members are observed as proteins that range from 15 to 20 kDa.

Synonyms

SPANX, SPANXC, SPANX-C, Sperm protein associated with the nucleus on the X chromosome C, Cancer-testis-associated protein CTp11, Cancer/testis antigen 11.3, CTP11, Nuclear associated protein SPAN Xc, SPANX family member C

Gene Name

SPANXC

UniProt

Q9NY87

Host

Rabbit

Reactivity

Human

Immunogen

This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near amino acids 25-50 of human SPANX protein.

Clonality

Polyclonal

Tissue Specificity

Detected in testis, melanoma and bladder carcinoma.

Applications

ELISA, WB

Field of Research

Cancer, Cell Biology, Tumor Antigens, Tumor Biomarkers, Tumor Immunology, Tumor-Associated Antigens

Purification

This affinity-purified antibody is directed against human SPANX proteins. The immunogen sequence is present within SPANX-A, SPANX-B, SPANX-C, SPANX-D and SPANX-N, but not present within SPANX-E. The product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with SPANX proteins from gorilla and chimpanzee. Reactivity against homologues from other sources is not known.

Concentration

1.0 mg/mL by UV absorbance at 280 nm

Form

Liquid (sterile filtered)

Molecular Weight

10982 MW

Shipping Conditions

Due to dry ice shipping issues, this product is temporarily not available to distributors outside of the United States.

Storage Conditions

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.

Fragment

IgG

Applications Notes

This affinity purified antibody has been tested for use in ELISA and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band ~97kDa.

Other Gene Names

Sperm protein associated with the nucleus on the X chromosome C

Subcellular Location

Cytoplasm. Nucleus. Associated with nuclear craters.

Frequently Asked Questions

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