Anti-GSDMC/Gasdermin C Antibody
Boster Bio Anti-GSDMC/Gasdermin C Antibody (Catalog # A13060) . Tested in WB applications. This antibody reacts with Human.
Product Specifications
Background
Belongs to the gasdermin family.<br><br>Watabe K., Jpn. J. Cancer Res. 92:140-151(2001).<br>Nusbaum C., Nature 439:331-335(2006).<br>The MGC Project Team, Genome Res. 14:2121-2127(2004).
Synonyms
Gasdermin-C; Melanoma-derived leucine zipper-containing extranuclear factor; GSDMC; MLZE
Gene Name
GSDMC
UniProt
Q9BYG8
Host
Rabbit
Reactivity
Human
Immunogen
Synthesized peptide derived from internal of human GSDMC.
Clonality
Polyclonal
Tissue Specificity
Expressed mainly in trachea and spleen (PubMed:11223543) . In the esophagus, expressed in differentiating cells and probably in differentiated cells. Also detected in gastric epithelium (PubMed:19051310) . .
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Dilution
Western blotting: 1:500~1:3000
Form
Liquid
Function
Upon activation, mediates pyroptosis. .
Molecular Weight
57692 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Gasdermin-C
Subcellular Location
Cytoplasm .
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