Anti-KLHL21 Monoclonal Antibody
Boster Bio Anti-KLHL21 Monoclonal Antibody catalog # A12797. Tested in IHC, WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Kelch-like protein 21; KLHL21; KIAA0469
Gene Name
KLHL21
UniProt
Q9UJP4
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant fragment of human KLHL21 expressed in E. Coli.
Clonality
Monoclonal
Clone
Clone: 2H4
Applications
WB, IHC
Purification
Ascitic fluid
Form
Liquid
Function
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR (KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR (KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome. .
Molecular Weight
66617 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Kelch-like protein 21
Subcellular Location
Cytoplasm, cytoskeleton, spindle . Localizes to the spindle midzone and targets CUL3 to this region.
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