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Anti-PLA2G4D Antibody

Boster Bio Anti-PLA2G4D Antibody (Catalog# A12553) . Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Rat, Mouse.

Product Specifications

Synonyms

PLA2G4D; Cytosolic phospholipase A2 delta; cPLA2-delta; Phospholipase A2 group IVD

Gene Name

PLA2G4D

UniProt

Q86XP0

Host

Rabbit

Reactivity

Human, Rat, Mouse

Immunogen

A peptide derived from human PLA2G4D. Immunogen sequence location: 531-580

Clonality

Polyclonal

Tissue Specificity

Expressed in stratified squamous epithelia, such as those in skin and cervix, but not in other tissues. Strongly expressed in the upper spinous layer of the psoriatic epidermis, expressed weakly and discontinuously in atopic dermatitis and mycosis fungoides, and not detected in the epidermis of normal skin.

Applications

IHC-P, IF (paraffin), ELISA

Field of Research

Cancer, Lipid Metabolism, Lipid Signaling, Metabolism, Signal Transduction, Signaling Pathway

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position. Not arachidonic acid-specific but has linoleic acid-specific activity. May play a role in inflammation in psoriatic lesions.

Molecular Weight

91952 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Cytosolic phospholipase A2 delta

Subcellular Location

Cytoplasm, cytosol.Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Translocates to membrane vesicles in a calcium-dependent fashion. Translocates to perinuclear regions upon ionomycin stimulation (By similarity) .

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