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Anti-KCNH3/Kv12.2 Antibody

Boster Bio Anti-KCNH3/Kv12.2 Antibody (Catalog # A11947) . Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits an outward current with fast inactivation. Channel properties may be modulated by cAMP and subunit assembly.<br><br>Miyake A., J. Biol. Chem. 274:25018-25025(1999).<br>Nagase T., DNA Res. 6:337-345(1999).

Synonyms

Potassium voltage-gated channel subfamily H member 3; Brain-specific eag-like channel 1; BEC1; Ether-a-go-go-like potassium channel 2; ELK channel 2; ELK2; Voltage-gated potassium channel subunit Kv12.2; KCNH3; KIAA1282

Gene Name

KCNH3

UniProt

Q9ULD8

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from Internal of human KCNH3.

Clonality

Polyclonal

Tissue Specificity

Detected only in brain, in particular in the telencephalon. Detected in the cerebral cortex, occipital pole, frontal and temporal lobe, putamen, amygdala, hippocampus and caudate nucleus.

Applications

WB

Field of Research

Cancer, Metabolism, Neuroscience, Neurotransmission, Plasma Membrane, Potassium Channels, Receptors / Channels, Signal Transduction

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits an outward current with fast inactivation. Channel properties may be modulated by cAMP and subunit assembly.

Molecular Weight

117129 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Potassium voltage-gated channel subfamily H member 3

Subcellular Location

Membrane; Multi-pass membrane protein.

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