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Anti-JM4 PRAF2 Antibody

Boster Bio Anti-JM4 PRAF2 Antibody (Catalog # A11750) . Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptic role in cerulenin-induced neuroblastoma apoptosis.<br><br>Koichi Kusuhara, J. Virol., Oct 1999; 73: 8112 - 8119. <br>Isis Rivera-Walsh, J. Biol. Chem., Aug 2000; 275: 25222.<br>Eric D. Tang, J. Biol. Chem., Sep 2003; 278: 37297 - 37305.<br>Isis Rivera-Walsh, J. Biol. Chem., Oct 2001; 276: 40385 - 40388.

Synonyms

PRA1 family protein 2; PRAF2; JM4

Gene Name

PRAF2

UniProt

O60831

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human JM4.

Clonality

Polyclonal

Tissue Specificity

Strong expression in the brain, small intestine, lung, spleen, and pancreas as well as in tumor tissues of the breast, colon, lung and ovary, with a weaker expression in normal tissues of the same patient. High expression in neuroblastic tumors. Strongly expressed in Purkinje cells and more moderately in cells of the molecular and the granular layers in the cerebellum. Detected in neuronal cells, but not in non- neuronal cells in the cerebral cortex, hippocampus, and lateral ventricles. .

Applications

WB, IHC

Field of Research

Protein Trafficking, Signal Transduction, Vesicle Transport

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptic role in cerulenin-induced neuroblastoma apoptosis. .

Molecular Weight

19258 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

PRA1 family protein 2

Subcellular Location

Endosome membrane ; Multi-pass membrane protein .

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