Anti-SR-6 HTR6 Antibody
Boster Bio Anti-SR-6 HTR6 Antibody catalog # A11122-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
5-hydroxytryptamine receptor 6;5-HT-6;5-HT6; Serotonin receptor 6; HTR6
Gene Name
HTR6
UniProt
P50406
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human 5-HT-6. AA range:221-270
Tissue Specificity
Expressed in several human brain regions, most prominently in the caudate nucleus.
Applications
WB
Purification
Immunogen affinity purified
Form
Liquid
Function
This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs (By similarity) . Controls pyramidal neurons migration during corticogenesis, through the regulation of CDK5 activity (By similarity) . Is an activator of TOR signaling (PubMed:23027611) . .
Molecular Weight
46954 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
5-hydroxytryptamine receptor 6
Subcellular Location
Cell membrane; Multi-pass membrane protein.
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