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FITC-GW3965

FITC-GW3965 is a fluorescence-labelled liver X receptor β (LXRβ) agonist GW3965. FITC-GW3965 is a tracer, that can be designed by replacing the trifluoromethyl of GW3965 with an amide to link the FITC. FITC-GW3965 can be used to study the function of LXRβ[1].

Product Specifications

CAS Number

2374144-23-5

UNSPSC

12171500

Target

LXR

Type

Dye Reagents

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/fitc-gw3965.html

Purity

98.0

Solubility

DMSO : ≥ 50 mg/mL

Smiles

O=C(CC1=CC(OCCCN(CC(C2=CC=CC=C2)C3=CC=CC=C3)CC4=CC(NC(CCCCCNC(NC5=CC=C6C(C(OC67C8=CC=C(C=C8OC9=CC(O)=CC=C97)O)=O)=C5)=S)=O)=CC=C4)=CC=C1)O

Molecular Formula

C59H56N4O9S

Molecular Weight

997.16

References & Citations

[1]Zhang Z, et al. Identify liver X receptor β modulator building blocks by developing a fluorescence polarization-based competition assay. Eur J Med Chem. 2019 Sep 15;178:458-467.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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