Anti-AGPAT5/Lpaat Epsilon Antibody

Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C15:0-C20:4 at the sn-1 position using C18:1-CoA as the acyl donor. Also acts on lysophosphatidylethanolamine using oleoyl-CoA, but not arachidonoyl-CoA, and lysophosphatidylinositol using arachidonoyl-CoA, but not oleoyl-CoA. Activity toward lysophosphatidylglycerol not detectable.<br><br>Wiemann S., Genome Res. 11:422-435(2001).<br>Ota T., Nat. Genet. 36:40-45(2004).<br>The MGC Project Team; Genome Res. 14:2121-2127(2004).

1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon;2.3.1.51;1-acylglycerol-3-phosphate O-acyltransferase 5;1-AGP acyltransferase 5;1-AGPAT 5; Lysophosphatidic acid acyltransferase epsilon; LPAAT-epsilon; AGPAT5

Cancer, Cancer Metabolism, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Metabolism of Lipids and Lipoproteins, Pathways and Processes, Signal Transduction

Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C15:0-C20:4 at the sn-1 position using C18:1-CoA as the acyl donor. Also acts on lysophosphatidylethanolamine using oleoyl-CoA, but not arachidonoyl-CoA, and lysophosphatidylinositol using arachidonoyl-CoA, but not oleoyl-CoA. Activity toward lysophosphatidylglycerol not detectable. .