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Anti-GUF1 Antibody

Boster Bio Anti-GUF1 Antibody (Catalog # A10058) . Tested in IHC applications. This antibody reacts with Human, Mouse.

Product Specifications

Background

Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner By similarity. HAMAP-Rule MF_03137<br><br>Ota T., Nat. Genet. 36:40-45(2004).<br>The MGC Project Team, Genome Res. 14:2121-2127(2004).<br>Vasilescu J., J. Proteome Res. 6:298-305(2007).

Synonyms

Translation factor GUF1, mitochondrial ;3.6.5.-; Elongation factor 4 homolog ; EF-4 ; GTPase GUF1 ; Ribosomal back-translocase ; GUF1

Gene Name

GUF1

UniProt

Q8N442

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from internal of human GUF1.

Clonality

Polyclonal

Applications

IHC

Field of Research

DNA/RNA, Epigenetics and Nuclear Signaling, Mito. Translation, Translation

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Immunohistochemistry: 1:50~1:100

Form

Liquid

Function

Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one- codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. .

Molecular Weight

74328 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Translation factor GUF1, mitochondrial

Subcellular Location

Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .

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