Anti-ELOVL3 Antibody

Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids (VLCFAs). Highest activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs.<br><br>The MGC Project Team; Genome Res. 14:2121-2127(2004).<br>Semina E.V., Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases.

Elongation of very long chain fatty acids protein 3 ;2.3.1.199 ;3-keto acyl-CoA synthase ELOVL3 ; Cold-inducible glycoprotein of 30 kDa; ELOVL fatty acid elongase 3 ; ELOVL FA elongase 3 ; Very long chain 3-ketoacyl-CoA synthase 3 ; Very long chain 3-oxoacyl-CoA synthase 3 ; ELOVL3 ; CIG30

Cancer, Cardiovascular, Fatty Acid Oxidation, Fatty Acids, Lipid Metabolism, Lipids/Lipoproteins, Metabolism, Pathways and Processes, Redox Metabolism, Signal Transduction

Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. .