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Anti-FRS3 Antibody

Boster Bio Anti-FRS3 Antibody (Catalog # A09227) . Tested in WB applications. This antibody reacts with Human.

Product Specifications

Background

Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.<br><br>Xu H., J. Biol. Chem. 273:17987-17990(1998).<br>Mungall A.J., Nature 425:805-811(2003).<br>The MGC Project Team; Genome Res. 14:2121-2127(2004).

Synonyms

Fibroblast growth factor receptor substrate 3; FGFR substrate 3; FGFR-signaling adaptor SNT2; Suc1-associated neurotrophic factor target 2; SNT-2; FRS3

Gene Name

FRS3

UniProt

O43559

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from internal of human FRS3.

Clonality

Polyclonal

Applications

WB

Field of Research

Adapters, Cytoplasmic, Growth Factors/Hormones, Protein Phosphorylation, Receptor Tyrosine Kinases, Signal Transduction, Tyrosine Kinases

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2. .

Molecular Weight

54462 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A09227

Product MSDS

https://www.bosterbio.com/msds?sku=A09227

Other Gene Names

Fibroblast growth factor receptor substrate 3

Subcellular Location

Membrane; Lipid-anchor.

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