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Anti-Docking protein 3 DOK3 Antibody

Boster Bio Anti-Docking protein 3 DOK3 Antibody (Catalog # A09019-1) . Tested in WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Background

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function By similarity.<br><br>Ota T., Nat. Genet. 36:40-45(2004).<br>The MGC Project Team, Genome Res. 14:2121-2127(2004).<br>Favre C., Genes Immun. 4:40-45(2003).

Synonyms

Docking protein 3; Downstream of tyrosine kinase 3; DOK3

Gene Name

DOK3

UniProt

Q7L591

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from internal of human DOK3.

Clonality

Polyclonal

Tissue Specificity

Expressed in spleen. .

Applications

WB

Field of Research

Adapters, Cancer, Cytoplasmic, G Protein Signaling, MAPK Pathway, Protein Phosphorylation, Ras Family, Serine/Threonine Kinases, Signal Transduction, Signaling Pathway, Small G Proteins

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function (By similarity) . .

Molecular Weight

53288 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Docking protein 3

Subcellular Location

Cytoplasm . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side .

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