Anti-PNPLA8/Ipla2 Gamma Antibody
Boster Bio Anti-PNPLA8/Ipla2 Gamma Antibody (Catalog # A08992) . Tested in WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Background
Calcium-independent phospholipase A2, which catalyzes the hydrolysis of the sn-2 position of glycerophospholipids, PtdSer and to a lower extent PtdCho. Cleaves membrane phospholipids.<br><br>Tanaka H., Biochem. Biophys. Res. Commun. 272:320-326(2000).<br>Mancuso D.J., J. Biol. Chem. 275:9937-9945(2000).<br>Hillier L.W., Nature 424:157-164(2003).
Synonyms
Calcium-independent phospholipase A2-gamma;3.1.1.5; Intracellular membrane-associated calcium-independent phospholipase A2 gamma; iPLA2-gamma; PNPLA-gamma; Patatin-like phospholipase domain-containing protein 8; iPLA2-2; PNPLA8; IPLA22, IPLA2G; BM-043
Gene Name
PNPLA8
UniProt
Q9NP80
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from internal of human PNPLA8.
Clonality
Polyclonal
Tissue Specificity
Expressed in parenchymal tissues including heart, skeletal muscle, placenta, brain, liver and pancreas. Also expressed in bronchial epithelial cells and kidney. Highest expression is observed in skeletal muscle and heart. .
Applications
WB
Field of Research
Cardiovascular, Fatty Acid Oxidation, Fatty Acids, Lipases, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Lipid Signaling, Lipids/Lipoproteins, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Redox Metabolism, Signal Transduction, Signaling Pathway
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Dilution
Western blotting: 1:500~1:3000
Form
Liquid
Function
Calcium-independent phospholipase A2, which catalyzes the hydrolysis of the sn-2 position of glycerophospholipids, PtdSer and to a lower extent PtdCho. Cleaves membrane phospholipids. .
Molecular Weight
88477 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Calcium-independent phospholipase A2-gamma
Subcellular Location
Endoplasmic reticulum membrane ; Single-pass membrane protein . Golgi apparatus membrane ; Single-pass membrane protein . Cytoplasm, perinuclear region .
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