Anti-PNPLA8/Ipla2 Gamma Antibody

Boster Bio Anti-PNPLA8/Ipla2 Gamma Antibody (Catalog # A08992) . Tested in WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Background

Calcium-independent phospholipase A2, which catalyzes the hydrolysis of the sn-2 position of glycerophospholipids, PtdSer and to a lower extent PtdCho. Cleaves membrane phospholipids.<br><br>Tanaka H., Biochem. Biophys. Res. Commun. 272:320-326(2000).<br>Mancuso D.J., J. Biol. Chem. 275:9937-9945(2000).<br>Hillier L.W., Nature 424:157-164(2003).

Synonyms

Calcium-independent phospholipase A2-gamma;3.1.1.5; Intracellular membrane-associated calcium-independent phospholipase A2 gamma; iPLA2-gamma; PNPLA-gamma; Patatin-like phospholipase domain-containing protein 8; iPLA2-2; PNPLA8; IPLA22, IPLA2G; BM-043

Gene Name

PNPLA8

UniProt

Q9NP80

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from internal of human PNPLA8.

Clonality

Polyclonal

Tissue Specificity

Expressed in parenchymal tissues including heart, skeletal muscle, placenta, brain, liver and pancreas. Also expressed in bronchial epithelial cells and kidney. Highest expression is observed in skeletal muscle and heart. .

Applications

Field of Research

Cardiovascular, Fatty Acid Oxidation, Fatty Acids, Lipases, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Lipid Signaling, Lipids/Lipoproteins, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Redox Metabolism, Signal Transduction, Signaling Pathway

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

Calcium-independent phospholipase A2, which catalyzes the hydrolysis of the sn-2 position of glycerophospholipids, PtdSer and to a lower extent PtdCho. Cleaves membrane phospholipids. .

Molecular Weight

88477 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Calcium-independent phospholipase A2-gamma

Subcellular Location

Endoplasmic reticulum membrane ; Single-pass membrane protein . Golgi apparatus membrane ; Single-pass membrane protein . Cytoplasm, perinuclear region .