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Anti-PJA2/Praja2 Antibody

Boster Bio Anti-PJA2/Praja2 Antibody catalog # A08677. Tested in WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

E3 ubiquitin-protein ligase Praja-2; Praja2;6.3.2.-; RING finger protein 131; PJA2; KIAA0438, RNF131

Gene Name

PJA2

UniProt

O43164

Host

Rabbit

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human PJA2. AA range:141-190

Applications

WB

Purification

Immunogen affinity purified

Form

Liquid

Function

Has E2-dependent E3 ubiquitin-protein ligase activity. Responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation. Essential for PKA- mediated long-term memory processes. .

Molecular Weight

78214 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

E3 ubiquitin-protein ligase Praja-2

Subcellular Location

Cytoplasm . Cell membrane . Endoplasmic reticulum membrane ; Peripheral membrane protein . Golgi apparatus membrane ; Peripheral membrane protein . Cell junction, synapse . Cell junction, synapse, postsynaptic cell membrane, postsynaptic density . Localizes at the cytoplasmic side of endoplasmic reticulum and Golgi apparatus. Expressed in the postsynaptic density region of synapses (By similarity) . Colocalizes with PRKAR2A and PRKAR2B in the cytoplasm and the cell membrane. .

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