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Anti-CHSS2 CHPF Antibody

Boster Bio Anti-CHSS2 CHPF Antibody (Catalog # A08402) . Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Has both beta-1, 3-glucuronic acid and beta-1, 4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Isoform 2 may facilitate PARK2 transport into the mitochondria. In collaboration with PARK2, isoform 2 may enhance cell viability and protect cells from oxidative stress.<br><br>Kitagawa H., J. Biol. Chem. 278:23666-23671(2003).<br>Yada T., J. Biol. Chem. 278:30235-30247(2003).<br>Clark H.F., Genome Res. 13:2265-2270(2003)

Synonyms

Chondroitin sulfate synthase 2;2.4.1.175;2.4.1.226; Chondroitin glucuronyltransferase 2; Chondroitin-polymerizing factor; ChPF; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II; N-acetylgalactosaminyltransferase 2; CHPF; CSS2; UNQ651/PRO1281

Gene Name

CHPF

UniProt

Q8IZ52

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from internal of human CHSS2.

Clonality

Polyclonal

Tissue Specificity

Ubiquitous. Highly expressed in pancreas, ovary, brain, heart, skeletal muscle, colon, kidney, liver, stomach, spleen and placenta. Isoform 3 is also ubiquitous. Isoform 2 is expressed in brain, spleen, ovary, testis, lung and peripheral mononuclear cells. .

Applications

WB, IHC, IF

Field of Research

Organelles, Subcellular Markers, Tags & Cell Markers

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Has both beta-1,3-glucuronic acid and beta-1,4-N- acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Isoform 2 may facilitate PARK2 transport into the mitochondria. In collaboration with PARK2, isoform 2 may enhance cell viability and protect cells from oxidative stress. .

Molecular Weight

85467 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Chondroitin sulfate synthase 2

Subcellular Location

Isoform 1: Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein . Cytoplasm, cytosol .

Frequently Asked Questions

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