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Anti-Ras and Rab interactor 3 RIN3 Antibody

Boster Bio Anti-Ras and Rab interactor 3 RIN3 Antibody (Catalog # A07997) . Tested in WB applications. This antibody reacts with Human.

Product Specifications

Background

Ras effector protein that functions as a guanine nucleotide exchange (GEF) for RAB5B and RAB31, by exchanging bound GDP for free GTP. Required for normal RAB31 function.<br><br>Heilig R., Nature 421:601-607(2003).<br>Ota T., Nat. Genet. 36:40-45(2004).<br>Saito K., J. Biol. Chem. 277:3412-3418(2002).

Synonyms

Ras and Rab interactor 3; Ras interaction/interference protein 3; RIN3

Gene Name

RIN3

UniProt

Q8TB24

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from internal of human RIN3.

Clonality

Polyclonal

Tissue Specificity

Widely expressed. .

Applications

WB

Field of Research

G Protein Signaling, Protein Trafficking, Regulators, Signal Transduction, Signaling Pathway, Small G Proteins, Vesicle Transport

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

Ras effector protein that functions as a guanine nucleotide exchange (GEF) for RAB5B and RAB31, by exchanging bound GDP for free GTP. Required for normal RAB31 function. .

Molecular Weight

107854 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Ras and Rab interactor 3

Subcellular Location

Cytoplasm . Cytoplasmic vesicle . Early endosome . Activation of tyrosine phosphorylation signaling induces translocation to cytoplasmic vesicles. .

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