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Anti-p56Dok-2 (Ab-299) Antibody

Boster Bio Anti-p56Dok-2 (Ab-299) Antibody (Catalog # A07956-2) . Tested in WB, IHC, IF applications. This antibody reacts with Human.

Product Specifications

Background

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation <br><br>Feng Cong, et, al. (1999) Mol. Cell. Biol; 19: 8314 - 8325. <br>Serge Lemay, et, al. (2000) Mol. Cell. Biol; 20: 2743 - 2754. <br>Ute Schaeper, et, al.(2000) J. Cell Biol; 149: 1419. <br>Miyuki Honma, et, al. (2006) Genes Cells; 11: 143 - 151.

Gene Name

DOK2

UniProt

O60496

Host

Rabbit

Reactivity

Human

Immunogen

Peptide sequence around aa.297~301 (G-E-Y-A-V) derived from Human p56Dok-2.

Clonality

Polyclonal

Applications

WB, IHC, IF

Field of Research

Adapters, Cancer, Cytoplasmic, MAPK Pathway, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction, Tyrosine Kinases

Purification

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/ml

Form

Liquid

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

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